08/19/08

Plumb's Veterinary Drug Handbook

Errata/Updates > 6th Edition

6th edition Errata/Updates will be posted here as they become available.

Date	Drug Monograph & Version	Error/Update
08/08	Dexmedetomidine Monograph: Desk p. 271; Pocket p. 363	Dosages for dogs should be mcg (ug)/kg not mg/kg. Correct dose for sedation and analgesia in dogs: 375 ug/m2 BSA IV and 500 ug/m2 BSA IM. Dosage for cats is correct. This error has been been corrected in subsequent printings.
08/08	Pamidronate Monograph: Desk p.688, Pocket p. 925	First dose listed for dogs "a" should say "For refractory hypercalcemia", NOT hyperglycemia. This error has been been corrected in subsequent printings.
12/08	Diphenhydramine Monograph: Desk p. 309, Pocket p. 414	The first dose listed for Guinea pigs (under Rabbits/Rodents/Small Mammals) should be 7.5 mg/kg PO. The incorrect dose (75mg/kg) is quoted correctly from the reference cited, but was a "typo" in that document. This error has been been corrected in subsequent printings.
1/09	Fipronil ± (S)-Methoprine Monograph: Desk p.1008, Pocket p. 1340	The applicator size for Frontline® Top Spot for Cats & Kittens, Frontline® Plus for Cats & Kittens, should be 0.5 mL , not 50 mL. The applicator sizes for Frontline® Top Spot for Dogs & Puppies is not 50 mL and should be listed the same as is for Frontline® Plus for Dogs & Puppies.
10/09	Firocoxib Monograph: Desk p. 388, Pocket p. 519	Dose for horses should be: 0.1 mg/kg (0.045 mg/lb), not 0.45 mg/lb.
10/09	Bromides Monograph: Desk p. 109, Pocket p. 146	In Client Information, last bullet point: replace: Dogs that cannot tolerate the GI effects (vomiting) of potassium chloride...with: Dogs that cannot tolerate the GI effects (vomiting) of potassium bromide...
10/09	Vancomycin Monograph: Desk p. 919, Pocket p. 1231	In prescriber highlights section add new bullet point: *Oral vancomycin is not absorbed systemically and is only useful for treating GI C. difficile* overgrowth**.
10/09	Captopril Monograph: Desk p.129, Pocket p. 174	In Overdose section: Change Dogs given 1.5 gm/kg orally... to: Dogs given 0.5 g/kg orally....
10/09	Insulin Monograph - Vetsulin® label dosage for dogs has changed. Desk p. 481 bottom left column, Pocket p. 646 middle of left column	Delete Dog Dosage starting with: Vetsulin®: The initial recommended dose is 1 Unit insulin /kg... with: Dogs: The initial recommended vetsulin® dose is 0.5 IU insulin/kg body weight. Initially, this dose should be given once daily concurrently with, or right after a meal. The veterinarian should re-evaluate the dog at appropriate intervals and adjust the dose based on clinical signs, urinalysis results, and glucose curve values until adequate glycemic control has been attained. In the US clinical study, glycemic control was considered adequate if an acceptable blood glucose curve was achieved (reduction in hyperglycemia and a nadir of 60-160 mg/dL), clinical signs of hyperglycemia (polyuria, polydipsia, and ketonuria) were improved, and hypoglycemia (blood glucose <50 mg/dL) was avoided. Twice daily therapy should be initiated if the duration of insulin action is determined to be inadequate. If twice daily treatment is initiated, the two doses should be 25% less than the once daily dose required to attain an acceptable nadir. For example, if a dog receiving 20 units of vetsulin® once daily has an acceptable nadir but inadequate duration of activity, the vetsulin® dose should be changed to 15 units twice daily.Further adjustments in dosage may be necessary with changes in the dog’s diet, body weight, or concomitant medication, or if the dog develops concurrent infection, inflammation, neoplasia, or an additional endocrine or other medical disorder. (Vetsulin® Product Label)
10/09	Insulin Monograph - Vetsulin® now labeled for use in cats; Desk p. 481-2, Pocket pp646-7	Add to Cat dosage section: Vetsulin®: The initial recommended dose in cats is 1 to 2 IU per injection. The injections should be given twice daily at approximately 12 hour intervals. For cats fed twice daily, the injections should be given concurrently with, or right after each meal. For cats fed ad libitum, no change in feeding schedule is needed. The veterinarian should re-evaluate the cat at appropriate intervals and adjust the dose based on clinical signs, urinalysis results, and glucose curve values until adequate glycemic control has been attained. Further adjustments in dosage may be necessary with changes in the cat’s diet, body weight, or concomitant medication, or if the cat develops concurrent infection, inflammation, neoplasia, or an additional endocrine or other medical disorder. (Vetsulin® Product Label)